---
format: "aidr-story-markdown/v1"
id: "7a7299e8243f3fd74a8ab32e993a16b5bbdca26265734d088845538f312babad"
canonical_url: "https://aidr.today/7a7299e8?lang=en"
title: "A Claude model autonomously chose a gene therapy and operated on a mouse brain with no human decision-making"
lang: "en"
requested_lang: "en"
available_langs: ["en","vi"]
translation_fallback: null
fallback_fields: []
published_at: "2026-10-30T19:42:59.000Z"
category: "Agents"
topics: ["anthropic","agent"]
source_urls: ["https://the-decoder.com/a-claude-model-autonomously-chose-a-gene-therapy-and-operated-on-a-mouse-brain-with-no-human-decision-making/","https://www.wired.com/story/an-ai-agent-did-brain-surgery-on-live-mouse/","https://genk.vn/ai-bat-dau-tranh-viec-cua-bac-si-phau-thuat-claude-sonnet-tu-chon-thuoc-quyet-dinh-cach-dieu-tri-roi-truc-tiep-mo-nao-165261031171756145.chn","https://news.ycombinator.com/item?id=50336138","https://twitter.com/OcanaSantero/status/2115442964574908902"]
summary: "An AI agent performed brain surgery on an epileptic mouse, autonomously choosing the drug, brain target, and injection coordinates without human decision-making. Lead researcher Ocana-Santero described it as the first time an AI agent has autonomously chosen a treatment and delivered it to a living mammal, though the agent refused to continue after a mid-surgery calibration error."
---

# A Claude model autonomously chose a gene therapy and operated on a mouse brain with no human decision\-making

> [Open the canonical story](<https://aidr.today/7a7299e8?lang=en>)

**Published:** 2026-10-30T19:42:59.000Z
**Category:** Agents
**Topics:** anthropic, agent

## Summary

An AI agent performed brain surgery on an epileptic mouse, autonomously choosing the drug, brain target, and injection coordinates without human decision\-making\. Lead researcher Ocana\-Santero described it as the first time an AI agent has autonomously chosen a treatment and delivered it to a living mammal, though the agent refused to continue after a mid\-surgery calibration error\.

## Sources

- [Story source](<https://the-decoder.com/a-claude-model-autonomously-chose-a-gene-therapy-and-operated-on-a-mouse-brain-with-no-human-decision-making/>)
- [Story source](<https://www.wired.com/story/an-ai-agent-did-brain-surgery-on-live-mouse/>)
- [Story source](<https://genk.vn/ai-bat-dau-tranh-viec-cua-bac-si-phau-thuat-claude-sonnet-tu-chon-thuoc-quyet-dinh-cach-dieu-tri-roi-truc-tiep-mo-nao-165261031171756145.chn>)
- [Discussion](<https://news.ycombinator.com/item?id=50336138>)
- [Story source](<https://twitter.com/OcanaSantero/status/2115442964574908902>)